Game Based Learning for Safety and Security Education

Safety and security education are important part of technology related education, because of recent number of increase in safety and security related incidents. Game based learning is an emerging and rapidly advancing forms of computer-assisted instruction. Game based learning for safety and security education enables students to learn concepts and skills without the risk of physical injury and security breach. In this paper, a pedestal grinder safety game and physical security game have been developed using industrial standard modeling and game development software. The average score of the knowledge test of grinder safety game was 82%, which is higher than traditional lecture only instruction method. In addition, the survey of physical security game shows 84% average satisfaction ratio from high school students who played the game during the summer camp. The results of these studies indicated that game based learning method can enhance students' learning without potential harm to the students

Ozone Inhalation Attenuated the Effects of Budesonide on Aspergillus fumigatus-Induced Airway Inflammation and Hyperreactivity in Mice.

Inhaled glucocorticoids form the mainstay of asthma treatment because of their anti-inflammatory effects in the lung. Exposure to the air pollutant ozone (O3) exacerbates chronic airways disease. We and others showed that presence of the epithelial-derived surfactant protein-D (SP-D) is important in immunoprotection against inflammatory changes including those induced by O3 inhalation in the airways. SP-D synthesis requires glucocorticoids. We hypothesized here that O3 exposure impairs glucocorticoid responsiveness (including SP-D production) in allergic airway inflammation. The effects of O3 inhalation and glucocorticoid treatment were studied in a mouse model of allergic asthma induced by sensitization and challenge with Aspergillus fumigatus (Af) in vivo. The role of O3 and glucocorticoids in regulation of SP-D expression was investigated in A549 and primary human type II alveolar epithelial cells in vitro. Budesonide inhibited airway hyperreactivity, eosinophil counts in the lung and bronchoalveolar lavage (BAL) and CCL11, IL-13, and IL-23p19 release in the BAL of mice sensitized and challenged with Af (p < 0.05). The inhibitory effects of budesonide were attenuated on inflammatory changes and were completely abolished on airway hyperreactivity after O3 exposure of mice sensitized and challenged with Af. O3 stimulated release of pro-neutrophilic mediators including CCL20 and IL-6 into the airways and impaired the inhibitory effects of budesonide on CCL11, IL-13 and IL-23. O3 also prevented budesonide-induced release of the immunoprotective lung collectin SP-D into the airways of allergen-challenged mice. O3 had a bi-phasic direct effect with early (<12 h) inhibition and late (>48 h) activation of SP-D mRNA (sftpd) in vitro. Dexamethasone and budesonide induced sftpd transcription and translation in human type II alveolar epithelial cells in a glucocorticoid receptor and STAT3 (an IL-6 responsive transcription factor) dependent manner. Our study indicates that O3 exposure counteracts the effects of budesonide on airway inflammation, airway hyperreactivity, and SP-D production. We speculate that impairment of SP-D expression may contribute to the acute O3-induced airway inflammation. Asthmatics exposed to high ambient O3 levels may become less responsive to glucocorticoid treatment during acute exacerbations

Shear viscosity, instability and the upper bound of the Gauss-Bonnet coupling constant

We compute the dimensionality dependence of $\eta/s$ for charged black branes with Gauss-Bonnet correction. We find that both causality and stability constrain the value of Gauss-Bonnet coupling constant to be bounded by 1/4 in the infinite dimensionality limit. We further show that higher dimensionality stabilize the gravitational perturbation. The stabilization of the perturbation in higher dimensional space-time is a straightforward consequence of the Gauss-Bonnet coupling constant bound.Comment: 16 pages,3 figures+3 tables,typos corrected, published versio

Acoustic black holes for relativistic fluids

We derive a new acoustic black hole metric from the Abelian Higgs model. In the non-relativistic limit, while the Abelian Higgs model becomes the Ginzburg-Landau model, the metric reduces to an ordinary Unruh type. We investigate the possibility of using (type I and II) superconductors as the acoustic black holes. We propose to realize experimental acoustic black holes by using spiral vortices solutions from the Navier-stokes equation in the non-relativistic classical fluids.Comment: 16 pages. typos corrected, contents expande

Evaluation of Game-Based Learning in Cybersecurity Education for High School Students

Game based learning is a new game play mechanism that the players explore various aspects of game play in a learning context designed by the instructor or the game designer. Nevertheless, general acceptance of game based learning as a new learning paradigm was deferred by a lack of well-controlled, large sample efficacy studies. To address the increasing need of cybersecurity workforce, this paper introduces a game based learning method for high school cybersecurity education. Purdue University Northwest launched GenCyber high school summer camps to about 200 high school students in Chicago metropolitan area. The survey conducted after the summer camp indicated that the game based learning for cybersecurity education was very effective in cybersecurity awareness training. Further analysis of survey data revealed that there is a gender difference in raising students' interests in cybersecurity and computer science education using game based learning method

Super-Yangian Y(gl(1|1)) and Its Oscillator Realization

On the basis of graded RTT formalism,the defining relation of the super-Yangian Y(gl(1|1)) is derived and its oscillator realization is constructed.Comment: 7 pages, latex, no figures, to appaer in the International Workshop on Frontiers in Quantum Field Theory,Urumqi,11-18,Augast,199

A Patternable and In Situ Formed Polymeric Zinc Blanket for a Reversible Zinc Anode in a Skin-Mountable Microbattery

Owing to their high safety and reversibility, aqueous microbatteries using zinc anodes and an acid electrolyte have emerged as promising candidates for wearable electronics. However, a critical limitation that prevents implementing zinc chemistry at the microscale lies in its spontaneous corrosion in an acidic electrolyte that causes a capacity loss of 40% after a ten-hour rest. Widespread anti-corrosion techniques, such as polymer coating, often retard the kinetics of zinc plating/stripping and lack spatial control at the microscale. Here, a polyimide coating that resolves this dilemma is reported. The coating prevents corrosion and hence reduces the capacity loss of a standby microbattery to 10%. The coordination of carbonyl oxygen in the polyimide with zinc ions builds up over cycling, creating a zinc blanket that minimizes the concentration gradient through the electrode/electrolyte interface and thus allows for fast kinetics and low plating/stripping overpotential. The polyimide's patternable feature energizes microbatteries in both aqueous and hydrogel electrolytes, delivering a supercapacitor-level rate performance and 400 stable cycles in the hydrogel electrolyte. Moreover, the microbattery is able to be attached to human skin and offers strong resistance to deformations, splashing, and external shock. The skin-mountable microbattery demonstrates an excellent combination of anti-corrosion, reversibility, and durability in wearables. © 2021 The Authors. Advanced Materials published by Wiley-VCH Gmb

Downscaling AMSR-2 Soil Moisture Data With Geographically Weighted Area-to-Area Regression Kriging

Soil moisture (SM) plays an important role in the land surface energy balance and water cycle. Microwave remote sensing has been applied widely to estimate SM. However, the application of such data is generally restricted because of their coarse spatial resolution. Downscaling methods have been applied to predict fine-resolution SM from original data with coarse spatial resolution. Commonly, SM is highly spatially variable and, consequently, such local spatial heterogeneity should be considered in a downscaling process. Here, a hybrid geostatistical approach, which integrates geographically weighted regression and area-to-area kriging, is proposed for downscaling microwave SM products. The proposed geographically weighted area-to-area regression kriging (GWATARK) method combines fine-spatial-resolution optical remote sensing data and coarse-spatial-resolution passive microwave remote sensing data, because the combination of both information sources has great potential for mapping fine-spatial-resolution near-surface SM. The GWATARK method was evaluated by producing downscaled SM at 1-km resolution from the 25-km-resolution daily AMSR-2 SM product. Comparison of the downscaled predictions from the GWATARK method and two benchmark methods on three sets of covariates with in situ observations showed that the GWATARK method is more accurate than the two benchmarks. On average, the root-mean-square error value decreased by 20%. The use of additional covariates further increased the accuracy of the downscaled predictions, particularly when using topography-corrected land surface temperature and vegetation-temperature condition index covariates

Octahedral Trifluoromagnesate, an Anomalous Metal Fluoride Species, Stabilizes the Transition State in a Biological Motor

Isoelectronic metal fluoride transition state analogue (TSA) complexes, MgF3- and AlF4-, have proven to be immensely useful in understanding mechanisms of biological motors utilizing phosphoryl transfer. Here we report a previously unobserved octahedral TSA complex, MgF3(H2O)-, in a 1.5 Å resolution Zika virus NS3 helicase crystal structure. 19F NMR provided independent validation and also the direct observation of conformational tightening resulting from ssRNA binding in solution. The TSA stabilizes the two conformations of motif V of the helicase that link ATP hydrolysis with mechanical work. DFT analysis further validated the MgF3(H2O)- species, indicating the significance of this TSA for studies of biological motors